In today’s rapidly evolving healthcare landscape, the integration of machine learning technology is driving fundamental transformations. Picture a future where wearable devices become indispensable allies, offering unprecedented precision in diagnosing medical conditions. This presentation delves deep into the realm of advanced and efficient neural network models, particularly tinyML, and their pivotal role in reshaping the future of medical diagnosis through long-term monitoring. Furthermore, personalization emerges as a crucial need that impacts the need and use around the medical devices design and technology. Continuously evolving and innovative models are refining on-edge performances, thereby enhancing the potential of the next generation of these devices. During this session, we will explore some of the novel and compatible tinyML models that have shown promising potential, discussing their implications and contributions to the future.